sequence homology

sequence homology
Strictly, refers to the situation where nucleic acid or protein sequences are similar because they have a common evolutionary origin. Often used loosely to indicate that sequences are very similar. Sequence similarity is observable; homology is an hypothesis based on observation.

Dictionary of molecular biology. 2004.

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  • Homology (biology) — For use of the term homologous in reference to chromosomes, see Homologous chromosomes. The principle of homology: The biological derivation relationship (shown by colors) of the various bones in the forelimbs of four vertebrates is known as… …   Wikipedia

  • homology regions — regions of immunoglobulin heavy and light chains containing about 110 amino acid residues and forming compact globular domains stabilized by one intrachain disulfide bond; they have a high degree of sequence homology and similar three dimensional …   Medical dictionary

  • Homology — may refer to:* Homology (anthropology), analogy between human beliefs, practices or artifacts due to genetic or historical connections. * Homology (biology): similar structures due to shared ancestry. * Homology (chemistry): a compound of a… …   Wikipedia

  • Homology directed repair — (HDR) is a mechanism in cells to repair double strand DNA lesions. This repair mechanism can only be used by the cell when there is a homologue piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. When the homologue… …   Wikipedia

  • Homology (mathematics) — In mathematics (especially algebraic topology and abstract algebra), homology (in Greek ὁμός homos identical ) is a certain general procedure to associate a sequence of abelian groups or modules with a given mathematical object such as a… …   Wikipedia

  • Sequence alignment — In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.[1]… …   Wikipedia

  • Homology theory — In mathematics, homology theory is the axiomatic study of the intuitive geometric idea of homology of cycles on topological spaces. It can be broadly defined as the study of homology theories on topological spaces. Simple explanation At the… …   Wikipedia

  • homology — noun (plural gies) Date: circa 1656 1. a similarity often attributable to common origin 2. a. likeness in structure between parts of different organisms (as the wing of a bat and the human arm) due to evolutionary differentiation from a… …   New Collegiate Dictionary

  • homology — The state of being homologous. h. of chains the degree of similarity between the base sequences of strands of two DNAs. SYN: h. of strands. DNA h. the degree (or percentage) of hybridization capable between the DNA of different microorganisms. h …   Medical dictionary

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